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KMID : 1190620120080010027
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Journal of the Korean Wound Care Society
2012 Volume.8 No. 1 p.27 ~ p.30
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A Treatment of Diabetic Gangrene Using Negative Pressure Wound Therapy and Regenerative Acellular Dermal Matrix in A Compromised Patie
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Choi Yim-Don
Jung Bo-Ra
Mim Kyoung-Ran
Park Eun-Soo
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Abstract
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Despite numerous advances, non-healing wounds continue to be a treatment challenge. The negative pressure wound therapy and regenerative acellular dermal matrix have been reported to minimize operative morbidity and speed up the healing time of various chronic wound. So we applied the negative pressure wound therapy (VAC?) and regenerative acellular dermal matrix (Pelnac?) for treatment of the intractable diabetic gangrene with infection, non-healthy granulation tissue, or systemic factor that could impair wound healing. The negative pressure wound therapy facilitated granulation tissue proliferation and eradication of any pre-existing infection. For adequate proliferation of granulation tissue, regenerative acellular dermal matrix is good material, especially preparing skin graft or flap coverage. It provides a favorable microenvironment for bioingrowth by promoting nutritional diffusion and cellular proliferation at the graft site. Diabetic Gangrene were healed by successively with this methods.
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KEYWORD
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Diabetic foot, Negative pressure wound therapy, Acellular dermal matrix
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